It was a weird moment for Dr. Jo Wilson… and all of us.

Over the course of 20 seasons,Grey’s Anatomyhas seen it all.

They could reverse it.

Skylar Astin and Camilla Luddington on ‘Grey’s Anatomy’

Skylar Astin and Camilla Luddington on ‘Grey’s Anatomy’.Steven Baffo/Getty

“It was instant love for me,” the actress recalled.

I’d be like, ‘No, this is the guy for Jo.'"

While Luddington remains onGrey’sand Capshawrecently reprised her role as Dr. Arizona Robbins, Astin has moved on.

Listen to Luddington, Capshaw, and Astin onCall It What It Isabove.